Blood-based CRC test more cost-effective than alternatives, study says

Blood-based colorectal cancer screening test Epi proColon was more cost-effective than other alternative screening options, according to a company release about a study published in the Journal of the National Cancer Institute.

Researchers compared Epi proColon to computed tomographic colonography, PillCam and Cologuard. Researchers compared clinical effectiveness through five different scenarios, including a scenario that assumed the Epi proColon missed 12 percent of advanced adenomas and 18 percent of CRC cases.

What they found:

1. Annual screening with Epi proColon had an incremental cost-effectiveness ratio of $63,253 for every quality-adjusted life year gained.

2. CTC every five years had a ratio of $1,092 and annual Cologuard screening had a ratio of $214,974.

3. Researchers used a "willingness-to-pay" threshold of $100,000 for quality-adjusted life years gained.

4. Epi proColon was more cost-effective than Cologuard in all scenarios, but the authors concluded that the best test was the "one that gets done."

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